"ANZ is an important market for CA. Therefore, it was essential we found the right candidate to continue delivering value to our customers and driving the business in ANZ," said CA's APJ president and general manager Martin Mackay.
"I firmly believe Janice's business acumen, market knowledge and experience leading teams to achieve sales, revenue and customer satisfaction targets make her the perfect fit for our team."
Cox was most recently a director of Telstra's managed customer segment.
She was subsequently appointed vice-president and general manager of the personal systems group,
Paul Falkenstein, her predecessor as managing director of CA ANZ, is staying on for a transition period before retiring after two decades with the company.
"I'd also like to thank Paul for his 20 years of dedication to CA," said Mackay
"During this time, he has been instrumental to the success of the business having held numerous regional-level roles as well as area management roles leading both our Japanese and Australian businesses.
"While I know there is a tropical island calling his name, I appreciate Paul's commitment to our ANZ employees, partners and customers as he works with Janice to ensure a smooth transition for all."