In a statement, NBN Co said the figures were based on a report it had commissioned from the Regional Australia Institute titled Mount Gambier Business Growth Opportunities.
The report was created using research from AlphaBeta's first national economic and social study of the impact of the NBN.
It said that Mount Gambier had a high percentage of professional workers (16%) and knowledge-intensive business services (2.8%) and this was an indication the region would be able to capitalise on digital facilities.
RAI chef executive Jack Archer said: "Mount Gambier has an enormous opportunity to build on traditional industries such as tourism, hospitality and retail services while building on new business opportunities to drive future economic growth.
“In particular, industries that rely on digital capabilities, such as large data transfer requirements and video conferencing will be able to leverage fast broadband to grow and become more competitive beyond the region."